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ENZYME

ENZYME entry: EC 3.4.11.5

Accepted Name
prolyl aminopeptidase
Alternative Name(s)
cytosol aminopeptidase V
proline aminopeptidase
proline iminopeptidase
Pro-X aminopeptidase
Reaction catalysed
Release of N-terminal proline from a peptide
Comment(s)
  • Present in the cytosol of mammalian and microbial cells.
  • In contrast to the mammalian form, the bacterial form of the enzyme hydrolyzes both polyproline and prolyl-2-naphthylamide.
  • The mammalian enzyme, which is not specific for prolyl bonds, is possibly identical with EC 3.4.11.1.
  • Belongs to peptidase family S33.
  • Formerly EC 3.4.1.4.
Cross-references
BRENDA3.4.11.5
EC2PDB3.4.11.5
ExplorEnz3.4.11.5
PRIAM enzyme-specific profiles3.4.11.5
KEGG Ligand Database for Enzyme Nomenclature3.4.11.5
IUBMB Enzyme Nomenclature3.4.11.5
IntEnz3.4.11.5
MEDLINEFind literature relating to 3.4.11.5
MetaCyc3.4.11.5
Rhea expert-curated reactions3.4.11.5
UniProtKB/Swiss-Prot
P30184, AMPL1_ARATHQ2QSB9, AMPL1_ORYSJQ10712, AMPL1_SOLLC
Q944P7, AMPL2_ARATHQ6K669, AMPL2_ORYSJQ42876, AMPL2_SOLLC
Q8RX72, AMPL3_ARATHP00727, AMPL_BOVINQ5V9F0, AMPL_DICDI
Q8SQZ7, AMPL_ENCCUP28838, AMPL_HUMANP86249, AMPL_MESAU
Q9CPY7, AMPL_MOUSEP28839, AMPL_PIGQ68FS4, AMPL_RAT
P31427, AMPL_SOLTUQ5XGB9, AMPL_XENTRA0A1L9WUM2, ANEH_ASPA1
W3XA95, PFMAB_PESFWP46547, PIP_AERSOP93732, PIP_ARATH
C0ZKI1, PIP_BREBNC7PDD8, PIP_CHIPDA5I3F5, PIP_CLOBH
Q184M8, PIP_CLOD6O05420, PIP_ELIMEA5FIF5, PIP_FLAJ1
Q5FMT1, PIP_LACACD5H0J3, PIP_LACCSQ1G8L9, PIP_LACDA
P46544, PIP_LACDEP46542, PIP_LACDLA8YWL3, PIP_LACH4
P52278, PIP_LACHEQ890D8, PIP_LACPLC7TMK0, PIP_LACRL
O83041, PIP_LEPBYQ03NE0, PIP_LEVBAP47266, PIP_MYCGE
P75092, PIP_MYCPNP42786, PIP_NEIGOQ9JUV1, PIP_NEIMA
Q9JZR6, PIP_NEIMBQ97UA2, PIP_SACS2O32449, PIP_SERMA
Q9S2L4, PIP_STRCOP96084, PIP_THEACQ97A76, PIP_THEVO
P46541, PIP_WEICAP52279, PIP_XANCIQ9PD69, PIP_XYLFA
Q87DF8, PIP_XYLFT

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-