Expasy logo

ENZYME

ENZYME entry: EC 3.4.11.5

PURL: https://purl.expasy.org/enzyme/EC/3.4.11.5
Accepted Name
prolyl aminopeptidase
Alternative Name(s)
cytosol aminopeptidase V
proline aminopeptidase
proline iminopeptidase
Pro-X aminopeptidase
Reaction catalysed
Release of N-terminal proline from a peptide
Comment(s)
  • Present in the cytosol of mammalian and microbial cells.
  • In contrast to the mammalian form, the bacterial form of the enzyme hydrolyzes both polyproline and prolyl-2-naphthylamide.
  • The mammalian enzyme, which is not specific for prolyl bonds, is possibly identical with EC 3.4.11.1.
  • Belongs to peptidase family S33.
  • Formerly EC 3.4.1.4.
Cross-references
Rhea expert-curated reactions3.4.11.5
ExplorEnz3.4.11.5
IUBMB Enzyme Nomenclature3.4.11.5
UniProtKB/Swiss-Prot
P30184, AMPL1_ARATHQ2QSB9, AMPL1_ORYSJQ10712, AMPL1_SOLLC
Q944P7, AMPL2_ARATHQ6K669, AMPL2_ORYSJO24022, AMPL2_SOLLC
Q8RX72, AMPL3_ARATHQ42876, AMPLN_SOLLCP00727, AMPL_BOVIN
Q5V9F0, AMPL_DICDIQ8SQZ7, AMPL_ENCCUP28838, AMPL_HUMAN
P86249, AMPL_MESAUQ9CPY7, AMPL_MOUSEP28839, AMPL_PIG
Q68FS4, AMPL_RATP31427, AMPL_SOLTUQ5XGB9, AMPL_XENTR
A0A1L9WUM2, ANEH_ASPA1W3XA95, PFMAB_PESFWP46547, PIP_AERSO
P93732, PIP_ARATHC0ZKI1, PIP_BREBNC7PDD8, PIP_CHIPD
A5I3F5, PIP_CLOBHQ184M8, PIP_CLOD6O05420, PIP_ELIME
A5FIF5, PIP_FLAJ1P46541, PIP_HEYCOQ5FMT1, PIP_LACAC
D5H0J3, PIP_LACCSQ1G8L9, PIP_LACDAP46544, PIP_LACDE
P46542, PIP_LACDLA8YWL3, PIP_LACH4P52278, PIP_LACHE
Q890D8, PIP_LACPLC7TMK0, PIP_LACRLO83041, PIP_LEPBY
Q03NE0, PIP_LEVBAP47266, PIP_MYCGEP75092, PIP_MYCPN
P42786, PIP_NEIGOQ9JUV1, PIP_NEIMAQ9JZR6, PIP_NEIMB
Q97UA2, PIP_SACS2O32449, PIP_SERMAQ9S2L4, PIP_STRCO
P96084, PIP_THEACQ97A76, PIP_THEVOP52279, PIP_XANCI
Q9PD69, PIP_XYLFAQ87DF8, PIP_XYLFT
BRENDA3.4.11.5
MetaCyc3.4.11.5
KEGG Ligand Database for Enzyme Nomenclature3.4.11.5
EC2PDB3.4.11.5
MEDLINEFind literature relating to 3.4.11.5

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-