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ENZYME entry: EC 3.4.11.7

Accepted Name
Glutamyl aminopeptidase.
Alternative Name(s)
Aminopeptidase A.
Angiotensinase A.
Aspartate aminopeptidase.
Glutamyl peptidase.
Membrane aminopeptidase II.
Reaction catalysed
Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide
Cofactor(s)
Zn(2+).
Comment(s)
  • Also acts on L-alpha-glutamyl-peptides.
  • Calcium-activated and generally membrane-bound.
  • Belongs to peptidase family M1.
Cross-references
PROSITEPDOC00129
BRENDA3.4.11.7
EC2PDB3.4.11.7
ExplorEnz3.4.11.7
PRIAM enzyme-specific profiles3.4.11.7
KEGG Ligand Database for Enzyme Nomenclature3.4.11.7
IUBMB Enzyme Nomenclature3.4.11.7
IntEnz3.4.11.7
MEDLINEFind literature relating to 3.4.11.7
MetaCyc3.4.11.7
Rhea expert-curated reactions3.4.11.7
UniProtKB/Swiss-Prot
D3UW23, AMPE_BITRH;  Q32LQ0, AMPE_BOVIN;  P0DQU2, AMPE_GLOBL;  
A5HUI5, AMPE_GLOBR;  Q07075, AMPE_HUMAN;  P16406, AMPE_MOUSE;  
Q95334, AMPE_PIG;  P50123, AMPE_RAT;  Q48677, PEPA_LACLM;  

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