A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.14.1

Accepted Name
Dipeptidyl-peptidase I.
Alternative Name(s)
Cathepsin C.
Cathepsin J.
Dipeptidyl aminopeptidase I.
Dipeptidyl transferase.
Reaction catalysed
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro
Comment(s)
  • Also polymerizes dipeptide amides, arylamides and esters at neutral pH.
  • Cl(-)-dependent lysosomal cysteine-type peptidase.
  • Belongs to peptidase family C1.
  • Formerly EC 3.4.4.9.
Cross-references
PROSITEPDOC00126
BRENDA3.4.14.1
EC2PDB3.4.14.1
ExplorEnz3.4.14.1
PRIAM enzyme-specific profiles3.4.14.1
KEGG Ligand Database for Enzyme Nomenclature3.4.14.1
IUBMB Enzyme Nomenclature3.4.14.1
IntEnz3.4.14.1
MEDLINEFind literature relating to 3.4.14.1
MetaCyc3.4.14.1
UniProtKB/Swiss-Prot
Q3ZCJ8, CATC_BOVIN;  O97578, CATC_CANLF;  P53634, CATC_HUMAN;  
Q60HG6, CATC_MACFA;  P97821, CATC_MOUSE;  Q5RB02, CATC_PONAB;  
P80067, CATC_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-