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ENZYME entry: EC 3.4.14.14

Accepted Name
[mycofactocin precursor peptide] peptidase.
Reaction catalysed
[mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + H2O <=> 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + [mycofactocin precursor peptide]-C-terminal glycine
Comment(s)
  • Requires Fe(2+) ad Zn(2+).
  • The enzyme participates in the biosynthesis of the enzyme cofactor mycofactocin.
  • It catalyzes cleavage of the mycofactocin precursor peptide following its modification by MftC to liberate its final two residues, which consist of a cross-linked valine-tyramine dipeptide.
Cross-references
BRENDA3.4.14.14
EC2PDB3.4.14.14
ExplorEnz3.4.14.14
PRIAM enzyme-specific profiles3.4.14.14
KEGG Ligand Database for Enzyme Nomenclature3.4.14.14
IUBMB Enzyme Nomenclature3.4.14.14
IntEnz3.4.14.14
MEDLINEFind literature relating to 3.4.14.14
MetaCyc3.4.14.14
Rhea expert-curated reactions3.4.14.14

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-