ENZYME entry: EC 3.4.14.14
| Accepted Name |
|---|
| [mycofactocin precursor peptide] peptidase.
|
| Reaction catalysed |
|---|
| [mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + H2O <=> 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + [mycofactocin precursor peptide]-C-terminal glycine |
| Comment(s) |
|---|
- Requires Fe(2+) ad Zn(2+).
- The enzyme participates in the biosynthesis of the enzyme cofactor
mycofactocin.
- It catalyzes cleavage of the mycofactocin precursor peptide following
its modification by MftC to liberate its final two residues, which
consist of a cross-linked valine-tyramine dipeptide.
|
| Cross-references |
|---|
| BRENDA | 3.4.14.14 |
| EC2PDB | 3.4.14.14 |
| ExplorEnz | 3.4.14.14 |
| PRIAM enzyme-specific profiles | 3.4.14.14 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.14.14 |
| IUBMB Enzyme Nomenclature | 3.4.14.14 |
| IntEnz | 3.4.14.14 |
| MEDLINE | Find literature relating to 3.4.14.14 |
| MetaCyc | 3.4.14.14 |
| Rhea expert-curated reactions | 3.4.14.14 |
| UniProtKB/Swiss-Prot |
|
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