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ENZYME entry: EC 3.4.16.5

Accepted Name
carboxypeptidase C
Alternative Name(s)
carboxypeptidase Y
cathepsin A
lysosomal protective protein
serine-type carboxypeptidase I
Reaction catalysed
Release of a C-terminal amino acid with broad specificity
Comment(s)
  • Carboxypeptidases of broad specificity with optimum pH 4.5-6.0, inhibited by the action of diisopropyl fluorophosphate, and sensitive to thiol-blocking reagents.
  • This enzyme is probably also identical to lysosomal tyrosine carboxypeptidase.
  • Belongs to peptidase family S10.
  • Formerly EC 3.4.12.1, EC 3.4.12.12, EC 3.4.16.1, EC 3.4.16.3 and EC 3.4.21.13.
Cross-references
BRENDA3.4.16.5
EC2PDB3.4.16.5
ExplorEnz3.4.16.5
PRIAM enzyme-specific profiles3.4.16.5
KEGG Ligand Database for Enzyme Nomenclature3.4.16.5
IUBMB Enzyme Nomenclature3.4.16.5
IntEnz3.4.16.5
MEDLINEFind literature relating to 3.4.16.5
MetaCyc3.4.16.5
Rhea expert-curated reactions3.4.16.5
UniProtKB/Swiss-Prot
P38109, ATG42_YEASTP07519, CBP1_HORVUP37890, CBP1_ORYSJ
P21529, CBP3_HORVUP37891, CBP3_ORYSJP11515, CBP3_WHEAT
C0NX46, CBPYA_AJECGA6RGA0, CBPYA_AJECNC5GEU5, CBPYA_AJEDR
D4AZ71, CBPYA_ARTBCE4USS9, CBPYA_ARTGPC5FWJ1, CBPYA_ARTOC
A1CUJ5, CBPYA_ASPCLB8NXS9, CBPYA_ASPFNQ5VJG9, CBPYA_ASPFU
A5AB21, CBPYA_ASPNCQ2TYA1, CBPYA_ASPORQ0CSD3, CBPYA_ASPTN
C5K1Y9, CBPYA_BLAGSA6RUD7, CBPYA_BOTFBQ2H9G6, CBPYA_CHAGB
C5P212, CBPYA_COCP7E3QR43, CBPYA_COLGMQ96VC4, CBPYA_EMENI
C7YQJ2, CBPYA_FUSV7E5A7I6, CBPYA_LEPMJA1DP75, CBPYA_NEOFI
Q7RXW8, CBPYA_NEUCRC1GXD8, CBPYA_PARBAC1GG77, CBPYA_PARBD
C0SGX7, CBPYA_PARBPB6HPP6, CBPYA_PENRWQ0V1R1, CBPYA_PHANO
B2AWD5, CBPYA_PODANA4RPY8, CBPYA_PYRO7B2WKF1, CBPYA_PYRTR
A7F4H5, CBPYA_SCLS1D1ZG13, CBPYA_SORMKB6QAN5, CBPYA_TALMQ
B8M044, CBPYA_TALSNB8XGR4, CBPYA_TRIEQQ5J6J0, CBPYA_TRIRU
A5YCB8, CBPYA_TRITOD4DLI1, CBPYA_TRIVHC4JNM2, CBPYA_UNCRE
D4ANB6, CBPYB_ARTBCP30574, CBPY_CANAXP52710, CBPY_KOMPG
O13849, CBPY_SCHPOP00729, CBPY_YEASTQ09991, CTS41_CAEEL
Q3MI05, PPGB_BOVINP10619, PPGB_HUMANP16675, PPGB_MOUSE
D4AQ54, SCPC_ARTBCD4B0Q6, SCPD_ARTBCD4AZG9, SCPE_ARTBC
D4ASE6, SCPF_ARTBCC9WMM5, VCP_APIME

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