ID 3.4.17.13 DE muramoyltetrapeptide carboxypeptidase. AN carboxypeptidase IIW. CA N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6- CA diaminoheptanedioyl-D-alanine + H2O = N-acetyl-D-glucosaminyl-N- CA acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioate + D-alanine. CC -!- Variants are known from various microorganisms. CC -!- Involved in peptidoglycan synthesis, catalyzing both decarboxylation CC and transpeptidation. CC -!- Stimulated by divalent cations such as magnesium and calcium, but not CC zinc. CC -!- Inhibited by thiol-blocking reagents, but unaffected by penicillin. DR Q8XDJ8, LDCA_ECO57 ; P59238, LDCA_ECOL6 ; P76008, LDCA_ECOLI ; DR Q9HTZ1, LDC_PSEAE ; P0AFV6, MEPS_ECO57 ; P0AFV5, MEPS_ECOL6 ; DR P0AFV4, MEPS_ECOLI ; P0AFV7, MEPS_SHIFL ; Q9VYX7, PGPSA_DROME; //