Expasy logo

ENZYME

ENZYME entry: EC 3.4.17.20

PURL: https://purl.expasy.org/enzyme/EC/3.4.17.20
Accepted Name
carboxypeptidase U
Alternative Name(s)
arginine carboxypeptidase
carboxypeptidase B2
carboxypeptidase R
plasma carboxypeptidase B
TAFI
thrombin-activatable fibrinolysis inhibitor
Reaction catalysed
Release of C-terminal Arg and Lys from a polypeptide
Comment(s)
  • Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U.
  • Activity similar to that of the more stable lysine carboxypeptidase, except no preference is shown for Lys over Arg.
  • Belongs to peptidase family M14.
Cross-references
BRENDA3.4.17.20
EC2PDB3.4.17.20
ExplorEnz3.4.17.20
KEGG Ligand Database for Enzyme Nomenclature3.4.17.20
IUBMB Enzyme Nomenclature3.4.17.20
MEDLINEFind literature relating to 3.4.17.20
MetaCyc3.4.17.20
Rhea expert-curated reactions3.4.17.20
UniProtKB/Swiss-Prot
Q2KIG3, CBPB2_BOVINQ96IY4, CBPB2_HUMANQ9JHH6, CBPB2_MOUSE
Q9EQV9, CBPB2_RAT

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.17.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-