ENZYME entry: EC 3.4.17.8
Accepted Name |
Muramoylpentapeptide carboxypeptidase.
|
Alternative Name(s) |
Carboxypeptidase D-alanyl-D-alanine. |
D-alanine carboxypeptidase. |
D-alanine-D-alanine-carboxypeptidase. |
D-alanyl-D-alanine carboxypeptidase. |
D-alanyl-D-alanine peptidase. |
DD-carboxypeptidase. |
DD-peptidase. |
PBP5. |
Penicillin binding protein 5. |
UDP-N-acetylmuramoyl-tetrapeptidyl-D-alanine alanine-hydrolase. |
Reaction catalysed |
Cleavage of the bond UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-|-D-alanine |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- Does not cleave the C-terminal D-alanine from the product of the
above reaction, UDP-N-acetyl-muramoyl-L-alanyl-gamma-D-glutamyl-6-
carboxy-L-lysyl-D-alanine.
- Competitively inhibited by penicillins and cephalosporins.
- Belongs to peptidase family M15.
- Formerly EC 3.4.12.6.
|
Cross-references |
BRENDA | 3.4.17.8 |
EC2PDB | 3.4.17.8 |
ExplorEnz | 3.4.17.8 |
PRIAM enzyme-specific profiles | 3.4.17.8 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.17.8 |
IUBMB Enzyme Nomenclature | 3.4.17.8 |
IntEnz | 3.4.17.8 |
MEDLINE | Find literature relating to 3.4.17.8 |
MetaCyc | 3.4.17.8 |
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