ENZYME

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.17.8

Accepted Name
Muramoylpentapeptide carboxypeptidase.
Alternative Name(s)
Carboxypeptidase D-alanyl-D-alanine.
D-alanine carboxypeptidase.
D-alanine-D-alanine-carboxypeptidase.
D-alanyl-D-alanine carboxypeptidase.
D-alanyl-D-alanine peptidase.
DD-carboxypeptidase.
DD-peptidase.
PBP5.
Penicillin binding protein 5.
UDP-N-acetylmuramoyl-tetrapeptidyl-D-alanine alanine-hydrolase.
Reaction catalysed
Cleavage of the bond UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-\|-D-alanine
Cofactor(s)
Zn(2+).
Comment(s)
Does not cleave the C-terminal D-alanine from the product of the above reaction, UDP-N-acetyl-muramoyl-L-alanyl-gamma-D-glutamyl-6- carboxy-L-lysyl-D-alanine. Competitively inhibited by penicillins and cephalosporins. Belongs to peptidase family M15. Formerly EC 3.4.12.6.
Cross-references
BRENDA	3.4.17.8
EC2PDB	3.4.17.8
ExplorEnz	3.4.17.8
PRIAM enzyme-specific profiles	3.4.17.8
KEGG Ligand Database for Enzyme Nomenclature	3.4.17.8
IUBMB Enzyme Nomenclature	3.4.17.8
IntEnz	3.4.17.8
MEDLINE	Find literature relating to 3.4.17.8
MetaCyc	3.4.17.8

Back to the Top