ENZYME entry: EC 3.4.19.2
Accepted Name |
Peptidyl-glycinamidase.
|
Alternative Name(s) |
Carboxyamidase. |
Peptidyl carboxyamidase. |
Reaction catalysed |
Cleavage of C-terminal glycinamide from polypeptides |
Comment(s) |
- Inactivates vasopressin and oxytocin by splitting off glycinamide.
- Also cleaves ester substrates of trypsin and chymotrypsin.
- Although glycinamide is by far the preferred leaving group, other
aminoacylamides may also be released, e.g. phenylalaninamide.
- The toad skin enzyme is inhibited by diisopropyl fluorophosphate.
- Formerly EC 3.4.15.2.
|
Cross-references |
BRENDA | 3.4.19.2 |
EC2PDB | 3.4.19.2 |
ExplorEnz | 3.4.19.2 |
PRIAM enzyme-specific profiles | 3.4.19.2 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.19.2 |
IUBMB Enzyme Nomenclature | 3.4.19.2 |
IntEnz | 3.4.19.2 |
MEDLINE | Find literature relating to 3.4.19.2 |
MetaCyc | 3.4.19.2 |
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.19.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-