ENZYME entry: EC 3.4.19.2
| Accepted Name |
|---|
| Peptidyl-glycinamidase.
|
| Alternative Name(s) |
|---|
| Carboxyamidase. |
| Peptidyl carboxyamidase. |
| Reaction catalysed |
|---|
| Cleavage of C-terminal glycinamide from polypeptides |
| Comment(s) |
|---|
- Inactivates vasopressin and oxytocin by splitting off glycinamide.
- Also cleaves ester substrates of trypsin and chymotrypsin.
- Although glycinamide is by far the preferred leaving group, other
aminoacylamides may also be released, e.g. phenylalaninamide.
- The toad skin enzyme is inhibited by diisopropyl fluorophosphate.
- Formerly EC 3.4.15.2.
|
| Cross-references |
|---|
| BRENDA | 3.4.19.2 |
| EC2PDB | 3.4.19.2 |
| ExplorEnz | 3.4.19.2 |
| PRIAM enzyme-specific profiles | 3.4.19.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.19.2 |
| IUBMB Enzyme Nomenclature | 3.4.19.2 |
| IntEnz | 3.4.19.2 |
| MEDLINE | Find literature relating to 3.4.19.2 |
| MetaCyc | 3.4.19.2 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.19.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-