ID 3.4.21.34 DE plasma kallikrein. AN kininogenin. AN serum kallikrein. CA Cleaves selectively Arg-|-Xaa and Lys-|-Xaa bonds, including Lys-|-Arg CA and Arg-|-Ser bonds in (human) kininogen to release bradykinin. CC -!- Formed from plasma prokallikrein (Fletcher factor) by factor XIIa. CC -!- Activates coagulation factors XII, VII and plasminogen. CC -!- Selective for Arg > Lys in P1, in small molecule substrates. CC -!- Belongs to peptidase family S1. CC -!- Formerly EC 3.4.4.21 and EC 3.4.21.8. DR Q2KJ63, KLKB1_BOVIN; P03952, KLKB1_HUMAN; P26262, KLKB1_MOUSE; DR P14272, KLKB1_RAT ; //