ID   3.4.21.68
DE   t-plasminogen activator.
AN   tissue plasminogen activator.
AN   tissue-type plasminogen activator.
AN   tPA.
CA   Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
CC   -!- From a wide variety of mammalian tissues, especially endothelial
CC       cells.
CC   -!- Secreted as a single chain precursor which is cleaved to a two-chain
CC       form by plasmin.
CC   -!- Activity is considerably enhanced by fibrin.
CC   -!- Belongs to peptidase family S1.
CC   -!- Formerly EC 3.4.21.31 and EC 3.4.99.26.
DR   Q28198, TPA_BOVIN  ;  P00750, TPA_HUMAN  ;  P11214, TPA_MOUSE  ;
DR   Q8SQ23, TPA_PIG    ;  Q5R8J0, TPA_PONAB  ;  P19637, TPA_RAT    ;
DR   P98119, URT1_DESRO ;  P15638, URT2_DESRO ;  P98121, URTB_DESRO ;
DR   P49150, URTG_DESRO ;
//