ID 3.4.21.69 DE activated protein C (thrombin-activated peptidase). AN activated blood coagulation factor XIV. AN autoprothrombin IIA. AN protein C (activated). CA Degradation of blood coagulation factors Va and VIIIa. CC -!- One of the gamma-carboxyglutamic acid-containing coagulation factors. CC -!- The enzyme plays an important role in regulating anticoagulation, CC inflammation, and cell death by proteolytically inactivating the CC blood coagulation factors factor Va and factor VIIIa. CC -!- Formed from protein C, the proenzyme that circulates in plasma, CC by the action of a complex of thrombin with thrombomodulin. CC -!- Protein C can also be activated by serine endopeptidases present in CC several snake venoms. CC -!- Belongs to peptidase family S1. DR P00745, PROC_BOVIN ; Q28278, PROC_CANLF ; Q28315, PROC_CAPHI ; DR Q28412, PROC_FELCA ; Q28380, PROC_HORSE ; P04070, PROC_HUMAN ; DR Q28506, PROC_MACMU ; P33587, PROC_MOUSE ; Q9GLP2, PROC_PIG ; DR Q28661, PROC_RABIT ; P31394, PROC_RAT ; //