ID 3.4.21.74 DE venombin A. CA Selective cleavage of Arg-|-Xaa bond in fibrinogen, to form fibrin, CA and release fibrinopeptide A. The specificity of further degradation of CA fibrinogen varies with species origin of the enzyme. CC -!- A somewhat thrombin-like enzyme from venoms of snakes of the CC viper/rattlesnake group. CC -!- Species variants of the enzyme include ancrod from Agkistrodon CC rhodostoma (Malayan pit viper), batroxobin from Bothrops atrox (South CC American pit viper) and crotalase from Crotalus adamanteus (Eastern CC diamondback rattlesnake). CC -!- Does not require activation by calcium. CC -!- Belongs to peptidase family S1. CC -!- Formerly EC 3.4.21.28, EC 3.4.21.29 and EC 3.4.21.30. DR P05620, VSP1_PROFL ; P81661, VSPA_BOTJA ; F8S114, VSPCR_CROAD; DR P26324, VSPF1_CALRH; P47797, VSPF2_CALRH; P04971, VSPF_BOTAT ; DR Q9PS28, VSPF_CERCE ; Q9PRP4, VSPF_LACMR ; P33589, VSPF_LACMU ; DR P0DJ86, VSPL_BOTLC ; //