ID 3.4.21.75 DE furin. AN dibasic processing enzyme. AN paired basic amino acid residue cleaving enzyme. AN prohormone convertase. CA Release of mature proteins from their proproteins by cleavage of -Arg- CA Xaa-Yaa-Arg-|-Zaa- bonds, where Xaa can be any amino acid and Yaa is Arg CA or Lys. Releases albumin, complement component C3 and von Willebrand CA factor from their respective precursors. CC -!- Activated by calcium. CC -!- Belongs to peptidase family S8. DR A0A044RE18, BLI_ONCVO ; P26016, FUR11_DROME; P30430, FUR1C_DROME; DR P30432, FUR2_DROME ; P29119, FURI1_XENLA; Q28193, FURIN_BOVIN; DR P09958, FURIN_HUMAN; P23188, FURIN_MOUSE; P23377, FURIN_RAT ; //