ID   3.4.21.78
DE   granzyme A.
AN   cytotoxic T-lymphocyte proteinase 1.
CA   Hydrolysis of proteins, including fibronectin, type IV collagen and
CA   nucleolin. Preferential cleavage: -Arg-|-Xaa-, -Lys-|-Xaa- >> -Phe-|-
CA   Xaa- in small molecule substrates.
CC   -!- From cytotoxic T lymphocyte granules.
CC   -!- The human enzyme does not cleave Phe-|-Xaa.
CC   -!- Belongs to peptidase family S1.
DR   Q7YRZ7, GRAA_BOVIN ;  P12544, GRAA_HUMAN ;  P11032, GRAA_MOUSE ;
//