ID 3.4.21.95 DE snake venom factor V activator. AN factor V-activating proteinase. AN RVV-V component. CA Fully activates human clotting factor V by a single cleavage at the 1545- CA Trp-Tyr-Leu-Arg-|-Ser-Asn-Asn-Gly-1552 bond. Cattle, but not rabbit, CA factor V is cleaved, and no other proteins of the clotting system are CA attacked. Esterase activity is observed on Bz-Arg-OEt and Tos-Arg-OMe, CA and amidase activity on Phe-pipecolyl-Arg-NHPhNO2. CC -!- Inhibited by diisopropyl fluorophosphate. CC -!- Belongs to peptidase family S1. DR P18964, VSPA_DABSI ; Q9PT41, VSPF5_MACLB; P18965, VSPG_DABSI ; //