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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.22.16

Accepted Name
Cathepsin H.
Alternative Name(s)
Aleurain.
Cathepsin B3.
Cathepsin BA.
N-benzoylarginine-beta-naphthylamide hydrolase.
Reaction catalysed
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|-Xaa bonds) as well as an endopeptidase
Comment(s)
  • Present in lysosomes of mammalian cells.
  • Because of the combination of endopeptidase and aminopeptidase activity it can be considered as 'endoaminopeptidase'.
  • Belongs to peptidase family C1.
Cross-references
PROSITEPDOC00126
BRENDA3.4.22.16
EC2PDB3.4.22.16
ExplorEnz3.4.22.16
PRIAM enzyme-specific profiles3.4.22.16
KEGG Ligand Database for Enzyme Nomenclature3.4.22.16
IUBMB Enzyme Nomenclature3.4.22.16
IntEnz3.4.22.16
MEDLINEFind literature relating to 3.4.22.16
MetaCyc3.4.22.16
UniProtKB/Swiss-Prot
Q8RWQ9, ALEUL_ARATH;  Q8H166, ALEU_ARATH;  P05167, ALEU_HORVU;  
Q3T0I2, CATH_BOVIN;  P09668, CATH_HUMAN;  P49935, CATH_MOUSE;  
O46427, CATH_PIG;  P00786, CATH_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.22.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-