A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.4.22.2
| Accepted Name |
|---|
| Papain.
|
| Alternative Name(s) |
|---|
| Papaya peptidase I. |
| Reaction catalysed |
|---|
| Hydrolysis of proteins with broad specificity for peptide bonds, but preference for an amino acid bearing a large hydrophobic side chain at the P2 position. Does not accept Val in P1' |
| Comment(s) |
|---|
- From latex of the papaya (Carica papaya).
- Inhibited by compound E-64 and proteins of the cystatin family.
- Belongs to peptidase family C1.
- Formerly EC 3.4.4.10.
|
| Cross-references |
|---|
| PROSITE | PDOC00126 |
| BRENDA | 3.4.22.2 |
| EC2PDB | 3.4.22.2 |
| ExplorEnz | 3.4.22.2 |
| PRIAM enzyme-specific profiles | 3.4.22.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.22.2 |
| IUBMB Enzyme Nomenclature | 3.4.22.2 |
| IntEnz | 3.4.22.2 |
| MEDLINE | Find literature relating to 3.4.22.2 |
| MetaCyc | 3.4.22.2 |
| UniProtKB/Swiss-Prot |
|
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