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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.22.29

Accepted Name
Picornain 2A.
Alternative Name(s)
Picornavirus endopeptidase 2A.
Poliovirus protease 2A.
Rhinovirus protease 2A.
Reaction catalysed
Selective cleavage of Tyr-|-Gly bond in the picornavirus polyprotein
Comment(s)
  • From entero- and rhinoviruses.
  • Smaller than the homologous virus picornain 3C.
  • Belongs to peptidase family C3.
Cross-references
BRENDA3.4.22.29
EC2PDB3.4.22.29
ExplorEnz3.4.22.29
PRIAM enzyme-specific profiles3.4.22.29
KEGG Ligand Database for Enzyme Nomenclature3.4.22.29
IUBMB Enzyme Nomenclature3.4.22.29
IntEnz3.4.22.29
MEDLINEFind literature relating to 3.4.22.29
MetaCyc3.4.22.29
UniProtKB/Swiss-Prot
P12915, POLG_BOVEV;  Q65900, POLG_CX16G;  Q9QF31, POLG_CX16T;  
P22055, POLG_CXA21;  P36290, POLG_CXA24;  P21404, POLG_CXA9;  
P08291, POLG_CXB1J;  Q9YLG5, POLG_CXB2O;  P03313, POLG_CXB3N;  
Q66282, POLG_CXB3W;  Q86887, POLG_CXB4E;  P08292, POLG_CXB4J;  
Q03053, POLG_CXB5P;  Q9QL88, POLG_CXB6S;  O91734, POLG_EC01F;  
Q9YLJ1, POLG_EC05N;  Q66474, POLG_EC06C;  Q66577, POLG_EC09B;  
Q66849, POLG_EC09H;  P29813, POLG_EC11G;  Q66575, POLG_EC12T;  
Q9WN78, POLG_EC30B;  P32537, POLG_HE701;  Q66478, POLG_HE71B;  
Q66479, POLG_HE71M;  Q66578, POLG_HPE1H;  Q9YID8, POLG_HPE23;  
O73556, POLG_HPE2W;  P03303, POLG_HRV14;  Q82122, POLG_HRV16;  
P23008, POLG_HRV1A;  P12916, POLG_HRV1B;  P04936, POLG_HRV2;  
Q82081, POLG_HRV3;  P07210, POLG_HRV8A;  O41174, POLG_PEV9U;  
P03300, POLG_POL1M;  P03301, POLG_POL1S;  P06210, POLG_POL2L;  
P23069, POLG_POL2W;  P06209, POLG_POL32;  P03302, POLG_POL3L;  
P16604, POLG_SVDVH;  P13900, POLG_SVDVU;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.22.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-