ID   3.4.22.33
DE   fruit bromelain.
CA   Hydrolysis of proteins with broad specificity for peptide bonds. Bz-Phe-
CA   Val-Arg-|-NHMec is a good synthetic substrate, but there is no action on
CA   Z-Arg-Arg-|-NHMec (cf. stem bromelain).
CC   -!- From the pineapple plant, Ananas comosus.
CC   -!- Scarcely inhibited by chicken cystatin.
CC   -!- Another cysteine endopeptidase, with similar action on small molecule
CC       substrates, pinguinain (formerly EC 3.4.99.18), is obtained from the
CC       related plant, Bromelia pinguin, but pinguinain differs from fruit
CC       bromelain in being inhibited by chicken cystatin.
CC   -!- Belongs to peptidase family C1.
CC   -!- Formerly EC 3.4.4.24, EC 3.4.22.4 and EC 3.4.22.5.
DR   O23791, BROM1_ANACO;
//