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ENZYME

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ENZYME entry: EC 3.4.22.34

Accepted Name
legumain
Alternative Name(s)
asparaginyl endopeptidase
bean endopeptidase
hemoglobinase
phaseolin
vicilin peptidohydrolase
Reaction catalysed
Hydrolysis of proteins and small molecule substrates at -Asn-|-Xaa- bonds
Comment(s)
  • Best known from legume seeds, the trematode Schistosoma mansoni and mammalian lysosomes.
  • Not inhibited by compound E-64.
  • Belongs to peptidase family C13.
Cross-references
BRENDA3.4.22.34
EC2PDB3.4.22.34
ExplorEnz3.4.22.34
PRIAM enzyme-specific profiles3.4.22.34
KEGG Ligand Database for Enzyme Nomenclature3.4.22.34
IUBMB Enzyme Nomenclature3.4.22.34
IntEnz3.4.22.34
MEDLINEFind literature relating to 3.4.22.34
MetaCyc3.4.22.34
Rhea expert-curated reactions3.4.22.34
UniProtKB/Swiss-Prot
P80527, HGLB1_FASHEP80530, HGLB2_FASHEP42665, HGLB_SCHJA
P09841, HGLB_SCHMAP49046, LEGU_CANENQ95M12, LGMN_BOVIN
Q99538, LGMN_HUMANQ4R4T8, LGMN_MACFAO89017, LGMN_MOUSE
Q5R5D9, LGMN_PONABQ9R0J8, LGMN_RATB8ASK4, VPE1_ORYSI
Q84LM2, VPE1_ORYSJP49047, VPEA_ARATHQ39044, VPEB_ARATH
Q9LJX8, VPED_ARATHQ39119, VPEG_ARATH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.22.-
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