ENZYME entry: EC 3.4.22.39

PURL: https://purl.expasy.org/enzyme/EC/3.4.22.39

Accepted Name

adenain

Reaction catalysed

Cleaves proteins of the adenovirus and its host cell at two consensus sites: -Yaa-Xaa-Gly-Gly-|-Xaa- and -Yaa-Xaa-Gly-Xaa-|-Gly- (in which Yaa is Met, Ile or Leu, and Xaa is any amino acid)

Comment(s)

A cysteine endopeptidase from adenoviruses.
Activity is greatly stimulated by the binding to the enzyme of an 11-residue peptide from the adenovirus capsid protein pre-VI at a site separate from the active site.
Belongs to peptidase family C5.

Cross-references

BRENDA

3.4.22.39

EC2PDB

3.4.22.39

ExplorEnz

3.4.22.39

KEGG Ligand Database for Enzyme Nomenclature

3.4.22.39

IUBMB Enzyme Nomenclature

3.4.22.39

MEDLINE

Find literature relating to 3.4.22.39

MetaCyc

3.4.22.39

Rhea expert-curated reactions

3.4.22.39

UniProtKB/Swiss-Prot

P03252, PRO_ADE02	P10381, PRO_ADE03	P07885, PRO_ADE04
P03253, PRO_ADE05	Q5TJ03, PRO_ADE09	P09569, PRO_ADE12
Q9WF19, PRO_ADE17	P11825, PRO_ADE40	P11826, PRO_ADE41
Q96629, PRO_ADEB2	P19119, PRO_ADEB3	O71150, PRO_ADEB4
P19151, PRO_ADEB7	O71070, PRO_ADEBA	P68984, PRO_ADECC
P68985, PRO_ADECR	P87563, PRO_ADECT	P68986, PRO_ADECU
O40958, PRO_ADEE2	Q9IIH4, PRO_ADEF1	P42672, PRO_ADEG1
Q9QM72, PRO_ADEG8	P30202, PRO_ADEM1	Q83906, PRO_ADEO7
Q84177, PRO_ADEP3	Q8JN66, PRO_ADES1

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.22.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
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