Expasy logo

ENZYME

ENZYME entry: EC 3.4.22.53

Accepted Name
calpain-2
Alternative Name(s)
calcium-activated neutral protease II
m-calpain
milli-calpain
Reaction catalysed
Broad endopeptidase specificity
Comment(s)
  • Cytosolic in animal cells.
  • The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC 3.4.22.52.
  • Belongs to peptidase family C2.
  • Formerly EC 3.4.22.17 and EC 3.4.24.5.
Cross-references
BRENDA3.4.22.53
EC2PDB3.4.22.53
ExplorEnz3.4.22.53
PRIAM enzyme-specific profiles3.4.22.53
KEGG Ligand Database for Enzyme Nomenclature3.4.22.53
IUBMB Enzyme Nomenclature3.4.22.53
IntEnz3.4.22.53
MEDLINEFind literature relating to 3.4.22.53
MetaCyc3.4.22.53
Rhea expert-curated reactions3.4.22.53
UniProtKB/Swiss-Prot
Q27971, CAN2_BOVINQ92178, CAN2_CHICKP17655, CAN2_HUMAN
Q9GLG1, CAN2_MACFAO08529, CAN2_MOUSEP43367, CAN2_PIG
P06814, CAN2_RABITQ07009, CAN2_RATA6NHC0, CAN8_HUMAN
Q91VA3, CAN8_MOUSEQ78EJ9, CAN8_RAT

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.22.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-