ID   3.4.22.69
DE   SARS coronavirus main proteinase.
AN   3C-like protease.
AN   3cLpro.
AN   coronavirus 3C-like protease.
AN   SARS coronavirus main protease.
AN   SARS-CoV 3CLpro enzyme.
AN   severe acute respiratory syndrome coronavirus main protease.
CA   TSAVLQ-|-SGFRK-NH2 and SGVTFQ-|-GKFKK the two peptides corresponding to
CA   the two self-cleavage sites of the SARS 3C-like proteinase are the two
CA   most reactive peptide substrates. The enzyme exhibits a strong preference
CA   for substrates containing Gln at P1 position and Leu at P2 position.
CC   -!- SARS coronavirus main protease is the key enzyme in SARS coronavirus
CC       replicase polyprotein processing.
CC   -!- Belongs to peptidase family C30.
DR   P0C6X7, R1AB_SARS  ;  P0DTD1, R1AB_SARS2 ;  P0C6F7, R1A_BC133  ;
DR   P0C6F5, R1A_BC279  ;  P0C6F8, R1A_BCHK3  ;  P0C6T4, R1A_BCHK4  ;
DR   P0C6T5, R1A_BCHK5  ;  P0C6T6, R1A_BCHK9  ;  P0C6T7, R1A_BCRP3  ;
DR   P0C6T8, R1A_CVBEN  ;  P0C6T9, R1A_CVBLU  ;  P0C6U0, R1A_CVBM   ;
DR   P0C6U1, R1A_CVBQ   ;  P0C6U3, R1A_CVHN1  ;  P0C6U4, R1A_CVHN2  ;
DR   P0C6U5, R1A_CVHN5  ;  P0C6U7, R1A_CVHOC  ;  P0C6U9, R1A_CVM2   ;
DR   P0C6V0, R1A_CVMA5  ;  P0C6V1, R1A_CVMJH  ;  K9N638, R1A_MERS1  ;
DR   P0C6U8, R1A_SARS   ;  P0DTC1, R1A_SARS2  ;
//