ID   3.4.23.1
DE   pepsin A.
AN   pepsin.
CA   Preferential cleavage: hydrophobic, preferably aromatic, residues in P1
CA   and P1' positions. Cleaves 1-Phe-|-Val-2, 4-Gln-|-His-5, 13-Glu-|-Ala-14,
CA   14-Ala-|-Leu-15, 15-Leu-|-Tyr-16, 16-Tyr-|-Leu-17, 23-Gly-|-Phe-24,
CA   24-Phe-|-Phe-25 and 25-Phe-|-Tyr-26 bonds in the B chain of insulin.
CC   -!- The predominant endopeptidase in the gastric juice of vertebrates,
CC       formed from pepsinogen A by limited proteolysis.
CC   -!- Belongs to peptidase family A1.
CC   -!- Formerly EC 3.4.4.1.
DR   P03954, PEPA1_MACFU;  P28712, PEPA1_RABIT;  P27677, PEPA2_MACFU;
DR   P27821, PEPA2_RABIT;  P0DJD8, PEPA3_HUMAN;  P27822, PEPA3_RABIT;
DR   P0DJD7, PEPA4_HUMAN;  P27678, PEPA4_MACFU;  P28713, PEPA4_RABIT;
DR   P0DJD9, PEPA5_HUMAN;  Q9D106, PEPA5_MOUSE;  P27823, PEPAF_RABIT;
DR   P00792, PEPA_BOVIN ;  Q9N2D4, PEPA_CALJA ;  Q9GMY6, PEPA_CANLF ;
DR   P00793, PEPA_CHICK ;  P11489, PEPA_MACMU ;  P00791, PEPA_PIG   ;
DR   Q9GMY7, PEPA_RHIFE ;  Q9GMY8, PEPA_SORUN ;  P81497, PEPA_SUNMU ;
DR   P13636, PEPA_URSTH ;
//