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ENZYME

ENZYME entry: EC 3.4.23.18

Accepted Name
aspergillopepsin I
Alternative Name(s)
aspergillopepsin A
aspergillopepsin F
aspergillopeptidase A
awamorin
proctase B
Protease type XIII
proteinase B
trypsinogen kinase
Reaction catalysed
Hydrolysis of proteins with broad specificity. Generally favors hydrophobic residues in P1 and P1', but also accepts Lys in P1, which leads to activation of trypsinogen. Does not clot milk
Comment(s)
  • Found in a variety of Aspergillus species (imperfect fungi): A.awamori, A.foetidus, A.fumigatus, A.kawachii, A.niger, A.oryzae, A.saitoi, and A.sojae.
  • Belongs to peptidase family A1.
  • Formerly EC 3.4.23.6.
Cross-references
BRENDA3.4.23.18
EC2PDB3.4.23.18
ExplorEnz3.4.23.18
PRIAM enzyme-specific profiles3.4.23.18
KEGG Ligand Database for Enzyme Nomenclature3.4.23.18
IUBMB Enzyme Nomenclature3.4.23.18
IntEnz3.4.23.18
MEDLINEFind literature relating to 3.4.23.18
MetaCyc3.4.23.18
Rhea expert-curated reactions3.4.23.18
UniProtKB/Swiss-Prot
D4ANC3, PEPA_ARTBCP17946, PEPA_ASPAWA1CBR4, PEPA_ASPCL
B0Y1V8, PEPA_ASPFCB8NLY9, PEPA_ASPFNP41748, PEPA_ASPFU
A2R3L3, PEPA_ASPNCP55325, PEPA_ASPNGQ06902, PEPA_ASPOR
P0CU33, PEPA_ASPOZA0A146F0J0, PEPA_ASPPEQ12567, PEPA_ASPPH
O93885, PEPA_EMENIA1DDK1, PEPA_NEOFID4D7C5, PEPA_TRIVH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.23.-
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