ENZYME entry: EC 3.4.23.18
| Accepted Name |
|---|
| Aspergillopepsin I.
|
| Alternative Name(s) |
|---|
| Aspergillopepsin A. |
| Aspergillopepsin F. |
| Aspergillopeptidase A. |
| Awamorin. |
| Proctase B. |
| Protease type XIII. |
| Proteinase B. |
| Trypsinogen kinase. |
| Reaction catalysed |
|---|
| Hydrolysis of proteins with broad specificity. Generally favors hydrophobic residues in P1 and P1', but also accepts Lys in P1, which leads to activation of trypsinogen. Does not clot milk |
| Comment(s) |
|---|
- Found in a variety of Aspergillus species (imperfect fungi):
A.awamori, A.foetidus, A.fumigatus, A.kawachii, A.niger, A.oryzae,
A.saitoi, and A.sojae.
- Belongs to peptidase family A1.
- Formerly EC 3.4.23.6.
|
| Cross-references |
|---|
| PROSITE | PDOC00128 |
| BRENDA | 3.4.23.18 |
| EC2PDB | 3.4.23.18 |
| ExplorEnz | 3.4.23.18 |
| PRIAM enzyme-specific profiles | 3.4.23.18 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.18 |
| IUBMB Enzyme Nomenclature | 3.4.23.18 |
| IntEnz | 3.4.23.18 |
| MEDLINE | Find literature relating to 3.4.23.18 |
| MetaCyc | 3.4.23.18 |
| Rhea expert-curated reactions | 3.4.23.18 |
| UniProtKB/Swiss-Prot |
| D4ANC3, PEPA_ARTBC; | P17946, PEPA_ASPAW; | A1CBR4, PEPA_ASPCL; |
| B0Y1V8, PEPA_ASPFC; | B8NLY9, PEPA_ASPFN; | P41748, PEPA_ASPFU; |
| A2R3L3, PEPA_ASPNC; | P55325, PEPA_ASPNG; | Q06902, PEPA_ASPOR; |
| P0CU33, PEPA_ASPOZ; | A0A146F0J0, PEPA_ASPPE; | Q12567, PEPA_ASPPH; |
| O93885, PEPA_EMENI; | A1DDK1, PEPA_NEOFI; | D4D7C5, PEPA_TRIVH; |
|
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