ENZYME entry: EC 3.4.23.18
Accepted Name |
Aspergillopepsin I.
|
Alternative Name(s) |
Aspergillopepsin A. |
Aspergillopepsin F. |
Aspergillopeptidase A. |
Awamorin. |
Proctase B. |
Protease type XIII. |
Proteinase B. |
Trypsinogen kinase. |
Reaction catalysed |
Hydrolysis of proteins with broad specificity. Generally favors hydrophobic residues in P1 and P1', but also accepts Lys in P1, which leads to activation of trypsinogen. Does not clot milk |
Comment(s) |
- Found in a variety of Aspergillus species (imperfect fungi):
A.awamori, A.foetidus, A.fumigatus, A.kawachii, A.niger, A.oryzae,
A.saitoi, and A.sojae.
- Belongs to peptidase family A1.
- Formerly EC 3.4.23.6.
|
Cross-references |
PROSITE | PDOC00128 |
BRENDA | 3.4.23.18 |
EC2PDB | 3.4.23.18 |
ExplorEnz | 3.4.23.18 |
PRIAM enzyme-specific profiles | 3.4.23.18 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.18 |
IUBMB Enzyme Nomenclature | 3.4.23.18 |
IntEnz | 3.4.23.18 |
MEDLINE | Find literature relating to 3.4.23.18 |
MetaCyc | 3.4.23.18 |
UniProtKB/Swiss-Prot |
D4ANC3, PEPA_ARTBC; | P17946, PEPA_ASPAW; | A1CBR4, PEPA_ASPCL; |
B0Y1V8, PEPA_ASPFC; | B8NLY9, PEPA_ASPFN; | P41748, PEPA_ASPFU; |
A2R3L3, PEPA_ASPNC; | P55325, PEPA_ASPNG; | Q06902, PEPA_ASPOR; |
P0CU33, PEPA_ASPOZ; | A0A146F0J0, PEPA_ASPPE; | Q12567, PEPA_ASPPH; |
O93885, PEPA_EMENI; | A1DDK1, PEPA_NEOFI; | D4D7C5, PEPA_TRIVH; |
|
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