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ENZYME entry: EC 3.4.23.19

Accepted Name
Aspergillopepsin II.
Alternative Name(s)
Aspergillus niger var. macrosporus aspartic proteinase.
Proctase A.
Proteinase A.
Reaction catalysed
Preferential cleavage in B chain of insulin: 3-Asn-|-Gln-4, 13-Gly-|-Ala-14, and 26-Tyr-|-Thr-27
Comment(s)
  • Isolated from Aspergillus niger var. macrosporus, distinct from aspergillopepsin I in specificity and insensitivity to pepstatin.
  • Belongs to peptidase family A4.
  • Formerly EC 3.4.23.6.
Cross-references
PROSITEPDOC00128
BRENDA3.4.23.19
EC2PDB3.4.23.19
ExplorEnz3.4.23.19
PRIAM enzyme-specific profiles3.4.23.19
KEGG Ligand Database for Enzyme Nomenclature3.4.23.19
IUBMB Enzyme Nomenclature3.4.23.19
IntEnz3.4.23.19
MEDLINEFind literature relating to 3.4.23.19
MetaCyc3.4.23.19
Rhea expert-curated reactions3.4.23.19
UniProtKB/Swiss-Prot
P24665, PRTA_ASPNG

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