ENZYME entry: EC 3.4.23.20
Accepted Name |
Penicillopepsin.
|
Alternative Name(s) |
Penicillium janthinellum aspartic protease. |
Peptidase A. |
Reaction catalysed |
Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving 20-Gly-|-Glu-21 in the B chain of insulin. Clots milk, and activates trypsinogen |
Comment(s) |
- From the imperfect fungus Penicillium janthinellum.
- Closely related enzymes have been isolated from P.roqueforti and
P.duponti.
- Belongs to peptidase family A1.
- Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.23.7.
|
Cross-references |
PROSITE | PDOC00128 |
BRENDA | 3.4.23.20 |
EC2PDB | 3.4.23.20 |
ExplorEnz | 3.4.23.20 |
PRIAM enzyme-specific profiles | 3.4.23.20 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.20 |
IUBMB Enzyme Nomenclature | 3.4.23.20 |
IntEnz | 3.4.23.20 |
MEDLINE | Find literature relating to 3.4.23.20 |
MetaCyc | 3.4.23.20 |
Rhea expert-curated reactions | 3.4.23.20 |
UniProtKB/Swiss-Prot |
|
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