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ENZYME

ENZYME entry: EC 3.4.23.24

Accepted Name
candidapepsin
Alternative Name(s)
Candida albicans aspartic proteinase
Reaction catalysed
Preferential cleavage at the carboxyl of hydrophobic amino acids, but fails to cleave 15-Leu-|-Tyr-16, 16-Tyr-|-Leu-17 and 24-Phe-|-Phe-25 of insulin B chain. Activates trypsinogen, and degrades keratin
Comment(s)
  • This endopeptidase from the imperfect yeast Candida albicans is inhibited by pepstatin, but not by methyl 2-diazoacetamido-hexanoate or 1,2-epoxy-3-(p-nitrophenoxy)propane.
  • Belongs to peptidase family A1.
  • Formerly EC 3.4.4.17 and EC 3.4.23.6.
Cross-references
BRENDA3.4.23.24
EC2PDB3.4.23.24
ExplorEnz3.4.23.24
PRIAM enzyme-specific profiles3.4.23.24
KEGG Ligand Database for Enzyme Nomenclature3.4.23.24
IUBMB Enzyme Nomenclature3.4.23.24
IntEnz3.4.23.24
MEDLINEFind literature relating to 3.4.23.24
MetaCyc3.4.23.24
Rhea expert-curated reactions3.4.23.24
UniProtKB/Swiss-Prot
Q5A651, CAR10_CANALP0CY27, CARP1_CANALC4YSF6, CARP1_CANAW
P0CY26, CARP1_CANAXP32951, CARP1_CANPAP0DJ06, CARP2_CANAL
C4YMJ3, CARP2_CANAWP0CS83, CARP2_CANAXP32950, CARP2_CANPA
P0CY29, CARP3_CANALC4YNQ5, CARP3_CANAWP0CY28, CARP3_CANAX
Q5A8N2, CARP4_CANALP43093, CARP4_CANAWP43094, CARP5_CANAL
Q5AC08, CARP6_CANALP43095, CARP6_CANAXQ59VH7, CARP7_CANAL
P43096, CARP7_CANAXQ5AEM6, CARP8_CANALO42778, CARP8_CANAX
Q59SU1, CARP9_CANALO42779, CARP9_CANAXQ00663, CARP_CANTR

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.23.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-