ENZYME

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.23.28

Accepted Name
Acrocylindropepsin.
Alternative Name(s)
Acrocylindrium proteinase.
Reaction catalysed
Preference for hydrophobic residue at P1 and P1'. Action on the B chain of insulin is generally similar to that of pepsin A, but it also cleaves 6-Leu-\|-Cys(SO(3)H)-7, 21-Glu-\|-Arg-22 and 3-Asn-\|-Gln-4, although not 4-Gln-\|-His-5
Comment(s)
From the imperfect fungus Acrocylindrium sp. Has a very low pH optimum on casein of 2.0. Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.99.1.
Cross-references
BRENDA	3.4.23.28
EC2PDB	3.4.23.28
ExplorEnz	3.4.23.28
PRIAM enzyme-specific profiles	3.4.23.28
KEGG Ligand Database for Enzyme Nomenclature	3.4.23.28
IUBMB Enzyme Nomenclature	3.4.23.28
IntEnz	3.4.23.28
MEDLINE	Find literature relating to 3.4.23.28
MetaCyc	3.4.23.28

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