ENZYME entry: EC 3.4.23.3
Accepted Name |
gastricsin.
|
Alternative Name(s) |
pepsin C. |
Reaction catalysed |
More restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|-Xaa bonds. High activity on hemoglobin |
Comment(s) |
- Formed from progastricsin, apparently in the gastric juice of most
vertebrates.
- In addition to the fundus, progastricsin is also secreted in antrum
and proximal duodenum.
- Seminal plasma contains a zymogen that is immunologically identical
with progastricsin.
- Belongs to peptidase family A1.
- Formerly EC 3.4.4.22.
|
Cross-references |
BRENDA | 3.4.23.3 |
EC2PDB | 3.4.23.3 |
ExplorEnz | 3.4.23.3 |
PRIAM enzyme-specific profiles | 3.4.23.3 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.3 |
IUBMB Enzyme Nomenclature | 3.4.23.3 |
IntEnz | 3.4.23.3 |
MEDLINE | Find literature relating to 3.4.23.3 |
MetaCyc | 3.4.23.3 |
Rhea expert-curated reactions | 3.4.23.3 |
UniProtKB/Swiss-Prot |
Q9N2D3, PEPC_CALJA; | Q64411, PEPC_CAVPO; | P20142, PEPC_HUMAN; |
P03955, PEPC_MACFU; | Q9D7R7, PEPC_MOUSE; | P30879, PEPC_PIG; |
Q9GMY2, PEPC_RABIT; | P04073, PEPC_RAT; | Q9GMY3, PEPC_RHIFE; |
Q9GMY4, PEPC_SORUN; | P81498, PEPC_SUNMU; |
|
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