ID 3.4.23.41 DE yapsin 1. AN aspartic proteinase 3. AN yeast aspartic protease 3. CA Hydrolyzes various precursor proteins with Arg or Lys in P1, and commonly CA Arg or Lys also in P2. The P3 amino acid is usually non-polar, CA but otherwise additional basic amino acids are favorable in both non- CA prime and prime positions. CC -!- Weakly inhibited by pepstatin. CC -!- Can partially substitute for kexin in a deficient strain of CC Saccharomyces cerevisiae. CC -!- The homologous product of the MKC7 gene (S.cerevisiae) has similar CC catalytic activity and has been termed yapsin 2. CC -!- Belongs to peptidase family A1. DR P53379, MKC7_YEAST ; P32329, YPS1_YEAST ; //