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ENZYME entry: EC 3.4.23.44

Accepted Name
nodavirus endopeptidase.
Alternative Name(s)
Black Beetle virus endopeptidase.
Flock House virus endopeptidase.
Reaction catalysed
Hydrolysis of an asparaginyl bond involved in the maturation of the structural protein of the virus, typically -Asn-|-Ala- or -Asn-|-Phe-
Comment(s)
  • A single aspartic residue is critical for activity, and inhibition by EDTA indicates that a metal ion is also important.
  • The enzyme is known from several nodaviruses that are pathogens of insects.
  • Belongs to peptidase family A6.
Cross-references
BRENDA3.4.23.44
EC2PDB3.4.23.44
ExplorEnz3.4.23.44
PRIAM enzyme-specific profiles3.4.23.44
KEGG Ligand Database for Enzyme Nomenclature3.4.23.44
IUBMB Enzyme Nomenclature3.4.23.44
IntEnz3.4.23.44
MEDLINEFind literature relating to 3.4.23.44
MetaCyc3.4.23.44
Rhea expert-curated reactions3.4.23.44
UniProtKB/Swiss-Prot
P04329, CAPSD_BBV;  P12869, CAPSD_BOOLV;  P12870, CAPSD_FHV;  
P12871, CAPSD_NODAM;  Q9J7Z0, CAPSD_PAV;  

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