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ENZYME entry: EC 3.4.24.1
Accepted Name |
atrolysin A.
|
Alternative Name(s) |
Crotalus atrox alpha-proteinase. |
Crotalus atrox metalloproteinase. |
hemorrhagic toxin a. |
Reaction catalysed |
Cleavage of 3-Asn-|-Gln-4, 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in insulin B chain. Removes C-terminal Leu from small peptides |
Comment(s) |
- A hemorrhagic endopeptidase of 68 kDa, one of six hemorrhagic toxins
in the venom of the western diamondback rattlesnake.
- The 60 kDa hemorrhagic toxin 1 of Crotalus ruber ruber shows
identical specificity.
- Belongs to peptidase family M12B.
|
Cross-references |
BRENDA | 3.4.24.1 |
EC2PDB | 3.4.24.1 |
ExplorEnz | 3.4.24.1 |
PRIAM enzyme-specific profiles | 3.4.24.1 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.1 |
IUBMB Enzyme Nomenclature | 3.4.24.1 |
IntEnz | 3.4.24.1 |
MEDLINE | Find literature relating to 3.4.24.1 |
MetaCyc | 3.4.24.1 |
Rhea expert-curated reactions | 3.4.24.1 |
UniProtKB/Swiss-Prot |
|
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