Home  |  Contact

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.24.14

Accepted Name
Procollagen N-endopeptidase.
Alternative Name(s)
Procollagen N-proteinase.
Reaction catalysed
Cleaves the N-propeptide of collagen chain alpha-1(I) at Pro-|-Gln and of alpha-1(II) and alpha-2(I) at Ala-|-Gln
Cofactor(s)
Zn(2+).
Comment(s)
  • Removes N-terminal propeptides of type I and II collagens prior to fibril assembly.
  • Does not cleave type III procollagen.
  • Belongs to peptidase family M12.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.14
EC2PDB3.4.24.14
ExplorEnz3.4.24.14
PRIAM enzyme-specific profiles3.4.24.14
KEGG Ligand Database for Enzyme Nomenclature3.4.24.14
IUBMB Enzyme Nomenclature3.4.24.14
IntEnz3.4.24.14
MEDLINEFind literature relating to 3.4.24.14
MetaCyc3.4.24.14
UniProtKB/Swiss-Prot
P79331, ATS2_BOVIN;  O95450, ATS2_HUMAN;  Q8C9W3, ATS2_MOUSE;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-