ID 3.4.24.18 DE meprin A. AN endopeptidase-2. CA Hydrolysis of protein and peptide substrates preferentially on carboxyl CA side of hydrophobic residues. CC -!- A membrane-bound metalloendopeptidase of rat and mouse kidney and CC intestinal brush borders, and salivary ducts. CC -!- Differences from EC 3.4.24.11 include insensitivity to phosphoramidon CC and thiorphan. CC -!- PABA-peptide hydrolase is a very similar enzyme found in human CC intestinal microvilli. CC -!- Belongs to peptidase family M12A. DR Q16819, MEP1A_HUMAN; P28825, MEP1A_MOUSE; Q64230, MEP1A_RAT ; //