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ENZYME entry: EC 3.4.24.21

Accepted Name
Astacin.
Alternative Name(s)
Astacus proteinase.
Crayfish small-molecule proteinase.
Reaction catalysed
Hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'
Cofactor(s)
Zn(2+).
Comment(s)
  • A digestive endopeptidase from the cardia of the crayfish Astacus fluviatilis.
  • Belongs to peptidase family M12A.
  • Formerly EC 3.4.99.6.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.21
EC2PDB3.4.24.21
ExplorEnz3.4.24.21
PRIAM enzyme-specific profiles3.4.24.21
KEGG Ligand Database for Enzyme Nomenclature3.4.24.21
IUBMB Enzyme Nomenclature3.4.24.21
IntEnz3.4.24.21
MEDLINEFind literature relating to 3.4.24.21
MetaCyc3.4.24.21
Rhea expert-curated reactions3.4.24.21
UniProtKB/Swiss-Prot
P07584, ASTA_ASTAS;  Q21179, NAS18_CAEEL;  Q18439, NAS8_CAEEL;  
D2KBH9, NAS8_STECR;  

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