Expasy logo

ENZYME

ENZYME entry: EC 3.4.24.23

PURL: https://purl.expasy.org/enzyme/EC/3.4.24.23
Accepted Name
matrilysin
Alternative Name(s)
matrin
matrix metalloproteinase 7
PUMP-1
putative (or punctuated) metalloproteinase-1
uterine metalloendopeptidase
Reaction catalysed
Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha2(I) > alpha1(I)
Comment(s)
  • Similar in specificity to stromelysin, but more active on azocoll.
  • Belongs to peptidase family M10B.
Cross-references
Rhea expert-curated reactions3.4.24.23
ExplorEnz3.4.24.23
IUBMB Enzyme Nomenclature3.4.24.23
UniProtKB/Swiss-Prot
P55032, MMP7_FELCAP09237, MMP7_HUMANQ10738, MMP7_MOUSE
P50280, MMP7_RAT
BRENDA3.4.24.23
MetaCyc3.4.24.23
KEGG Ligand Database for Enzyme Nomenclature3.4.24.23
EC2PDB3.4.24.23
MEDLINEFind literature relating to 3.4.24.23

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-