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ENZYME entry: EC 3.4.24.24

Accepted Name
Gelatinase A.
Alternative Name(s)
72-kDa gelatinase.
Matrix metalloproteinase 2.
Type IV collagenase.
Reaction catalysed
Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln
Cofactor(s)
Ca(2+); Zn(2+).
Comment(s)
Belongs to peptidase family M10B.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.24
EC2PDB3.4.24.24
ExplorEnz3.4.24.24
PRIAM enzyme-specific profiles3.4.24.24
KEGG Ligand Database for Enzyme Nomenclature3.4.24.24
IUBMB Enzyme Nomenclature3.4.24.24
IntEnz3.4.24.24
MEDLINEFind literature relating to 3.4.24.24
MetaCyc3.4.24.24
Rhea expert-curated reactions3.4.24.24
UniProtKB/Swiss-Prot
Q9GLE5, MMP2_BOVIN;  Q90611, MMP2_CHICK;  P08253, MMP2_HUMAN;  
P33434, MMP2_MOUSE;  P50757, MMP2_RABIT;  P33436, MMP2_RAT;  

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