A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.4.24.27
| Accepted Name |
|---|
| Thermolysin.
|
| Alternative Name(s) |
|---|
| Bacillus thermoproteolyticus neutral proteinase. |
| Reaction catalysed |
|---|
| Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe |
| Cofactor(s) |
|---|
| Ca(2+); Zn(2+).
|
| Comment(s) |
|---|
- A thermostable extracellular metalloendopeptidase containing four
calcium ions.
- Enzymes that may be species variants of thermolysin are reported from
Micrococcus caseolyticus and Aspergillus oryzae.
- Closely related but distinct enzymes are aeromonolysin, pseudolysin,
bacillolysin, aureolysin and mycolysin.
- Belongs to peptidase family M4.
- Formerly EC 3.4.24.4.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.27 |
| EC2PDB | 3.4.24.27 |
| ExplorEnz | 3.4.24.27 |
| PRIAM enzyme-specific profiles | 3.4.24.27 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.27 |
| IUBMB Enzyme Nomenclature | 3.4.24.27 |
| IntEnz | 3.4.24.27 |
| MEDLINE | Find literature relating to 3.4.24.27 |
| MetaCyc | 3.4.24.27 |
| UniProtKB/Swiss-Prot |
|
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