Home  |  Contact
Due to maintenance work, this service will be unavailable Mon Feb 13 between 07:00 and 09:30 - CET. Apologies for the inconvenience.

ENZYME entry: EC 3.4.24.27

Accepted Name
thermolysin.
Alternative Name(s)
Bacillus thermoproteolyticus neutral proteinase.
Reaction catalysed
Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe
Comment(s)
  • A thermostable extracellular metalloendopeptidase containing four calcium ions.
  • Enzymes that may be species variants of thermolysin are reported from Micrococcus caseolyticus and Aspergillus oryzae.
  • Closely related but distinct enzymes are aeromonolysin, pseudolysin, bacillolysin, aureolysin and mycolysin.
  • Belongs to peptidase family M4.
  • Formerly EC 3.4.24.4.
Cross-references
BRENDA3.4.24.27
EC2PDB3.4.24.27
ExplorEnz3.4.24.27
PRIAM enzyme-specific profiles3.4.24.27
KEGG Ligand Database for Enzyme Nomenclature3.4.24.27
IUBMB Enzyme Nomenclature3.4.24.27
IntEnz3.4.24.27
MEDLINEFind literature relating to 3.4.24.27
MetaCyc3.4.24.27
Rhea expert-curated reactions3.4.24.27
UniProtKB/Swiss-Prot
Q43880, THER_ALIAC;  Q59193, THER_BACCL;  Q59223, THER_BACSO;  
P00800, THER_BACTH;  P43133, THER_GEOSE;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-