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ENZYME entry: EC 3.4.24.31

Accepted Name
Mycolysin.
Alternative Name(s)
Pronase component.
Streptomyces griseus neutral proteinase.
Reaction catalysed
Preferential cleavage of bonds with hydrophobic residues in P1'
Cofactor(s)
Zn(2+).
Comment(s)
  • The enzyme has been characterized from the bacteria Streptomyces griseus, S.
  • naraensis, and S.
  • cacaoi.
  • Specificity is similar to that of thermolysin, but much more sensitive to inhibition by sulfanylacetyl-Phe-Leu.
  • Belongs to peptidase family M5.
  • Formerly EC 3.4.24.4.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.31
EC2PDB3.4.24.31
ExplorEnz3.4.24.31
PRIAM enzyme-specific profiles3.4.24.31
KEGG Ligand Database for Enzyme Nomenclature3.4.24.31
IUBMB Enzyme Nomenclature3.4.24.31
IntEnz3.4.24.31
MEDLINEFind literature relating to 3.4.24.31
MetaCyc3.4.24.31
Rhea expert-curated reactions3.4.24.31
UniProtKB/Swiss-Prot
P20910, MYCO_STRCI

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