ENZYME entry: EC 3.4.24.41
Accepted Name |
Atrolysin B.
|
Alternative Name(s) |
Crotalus atrox metalloendopeptidase b. |
Hemorrhagic toxin b. |
Ht-b. |
Reaction catalysed |
Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 of insulin B chain. Identical to the cleavage of insulin B chain by atrolysin C. Also cleaves Xaa-|-Ser bonds in glucagon |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- From the venom of the western diamondback rattlesnake (Crotalus
atrox).
- Belongs to peptidase family M12B.
|
Cross-references |
PROSITE | PDOC00129 |
BRENDA | 3.4.24.41 |
EC2PDB | 3.4.24.41 |
ExplorEnz | 3.4.24.41 |
PRIAM enzyme-specific profiles | 3.4.24.41 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.41 |
IUBMB Enzyme Nomenclature | 3.4.24.41 |
IntEnz | 3.4.24.41 |
MEDLINE | Find literature relating to 3.4.24.41 |
MetaCyc | 3.4.24.41 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-