ENZYME entry: EC 3.4.24.43
Accepted Name |
Atroxase.
|
Reaction catalysed |
Cleavage of 5-His-|-Leu-6, 9-Ser-|-His-10, 10-His-|-Leu-11, 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in insulin B chain |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- A nonhemorrhagic endopeptidase from the venom of the western
diamondback rattlesnake (Crotalus atrox).
- Cleaves fibrinogen.
- Belongs to peptidase family M12B.
|
Cross-references |
PROSITE | PDOC00129 |
BRENDA | 3.4.24.43 |
EC2PDB | 3.4.24.43 |
ExplorEnz | 3.4.24.43 |
PRIAM enzyme-specific profiles | 3.4.24.43 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.43 |
IUBMB Enzyme Nomenclature | 3.4.24.43 |
IntEnz | 3.4.24.43 |
MEDLINE | Find literature relating to 3.4.24.43 |
MetaCyc | 3.4.24.43 |
Rhea expert-curated reactions | 3.4.24.43 |
UniProtKB/Swiss-Prot |
|
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