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ENZYME entry: EC 3.4.24.43

Accepted Name
Atroxase.
Reaction catalysed
Cleavage of 5-His-|-Leu-6, 9-Ser-|-His-10, 10-His-|-Leu-11, 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in insulin B chain
Cofactor(s)
Zn(2+).
Comment(s)
  • A nonhemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox).
  • Cleaves fibrinogen.
  • Belongs to peptidase family M12B.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.43
EC2PDB3.4.24.43
ExplorEnz3.4.24.43
PRIAM enzyme-specific profiles3.4.24.43
KEGG Ligand Database for Enzyme Nomenclature3.4.24.43
IUBMB Enzyme Nomenclature3.4.24.43
IntEnz3.4.24.43
MEDLINEFind literature relating to 3.4.24.43
MetaCyc3.4.24.43
UniProtKB/Swiss-Prot
Q91401, VM1AT_CROAT

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