ENZYME entry: EC 3.4.24.45
Accepted Name |
Atrolysin F.
|
Alternative Name(s) |
Crotalus atrox metalloendopeptidase f. |
Hemorrhagic toxin f. |
Reaction catalysed |
Cleavage of 2-Val-|-Asn-3, 4-Gln-|-His-5, 6-Leu-|-Cys-7, 10-His-|-Leu-11, 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 bonds in insulin B chain |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- Hemorrhagic endopeptidase from the venom of the western diamondback
rattlesnake (Crotalus atrox).
- Digests the gamma chain of fibrinogen.
- Belongs to peptidase family M12B.
|
Cross-references |
PROSITE | PDOC00129 |
BRENDA | 3.4.24.45 |
EC2PDB | 3.4.24.45 |
ExplorEnz | 3.4.24.45 |
PRIAM enzyme-specific profiles | 3.4.24.45 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.45 |
IUBMB Enzyme Nomenclature | 3.4.24.45 |
IntEnz | 3.4.24.45 |
MEDLINE | Find literature relating to 3.4.24.45 |
MetaCyc | 3.4.24.45 |
Rhea expert-curated reactions | 3.4.24.45 |
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