ENZYME entry: EC 3.4.24.45
| Accepted Name |
|---|
| Atrolysin F.
|
| Alternative Name(s) |
|---|
| Crotalus atrox metalloendopeptidase f. |
| Hemorrhagic toxin f. |
| Reaction catalysed |
|---|
| Cleavage of 2-Val-|-Asn-3, 4-Gln-|-His-5, 6-Leu-|-Cys-7, 10-His-|-Leu-11, 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 bonds in insulin B chain |
| Cofactor(s) |
|---|
| Zn(2+).
|
| Comment(s) |
|---|
- Hemorrhagic endopeptidase from the venom of the western diamondback
rattlesnake (Crotalus atrox).
- Digests the gamma chain of fibrinogen.
- Belongs to peptidase family M12B.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.45 |
| EC2PDB | 3.4.24.45 |
| ExplorEnz | 3.4.24.45 |
| PRIAM enzyme-specific profiles | 3.4.24.45 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.45 |
| IUBMB Enzyme Nomenclature | 3.4.24.45 |
| IntEnz | 3.4.24.45 |
| MEDLINE | Find literature relating to 3.4.24.45 |
| MetaCyc | 3.4.24.45 |
| Rhea expert-curated reactions | 3.4.24.45 |
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