ENZYME entry: EC 3.4.24.48
Accepted Name |
Ruberlysin.
|
Alternative Name(s) |
Crotalus ruber metalloendopeptidase II. |
Hemorrhagic metalloproteinase HT-2. |
Hemorrhagic toxin II. |
Reaction catalysed |
Cleavage of 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 bonds of the B chain of insulin, His-|-Pro, Pro-|-Phe, and Trp-|-Ser of angiotensin I, and Gly-|-Phe of Met enkephalin |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- Hemorrhagic endopeptidase from the venom of the red rattlesnake
(Crotalus ruber ruber).
- Cleaves fibrinogen.
- Belongs to peptidase family M12B.
|
Cross-references |
PROSITE | PDOC00129 |
BRENDA | 3.4.24.48 |
EC2PDB | 3.4.24.48 |
ExplorEnz | 3.4.24.48 |
PRIAM enzyme-specific profiles | 3.4.24.48 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.48 |
IUBMB Enzyme Nomenclature | 3.4.24.48 |
IntEnz | 3.4.24.48 |
MEDLINE | Find literature relating to 3.4.24.48 |
MetaCyc | 3.4.24.48 |
Rhea expert-curated reactions | 3.4.24.48 |
UniProtKB/Swiss-Prot |
|
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