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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.24.51

Accepted Name
Ophiolysin.
Alternative Name(s)
Ophiophagus metalloendopeptidase.
Reaction catalysed
Cleavage of 3-Asn-|-Gln-4, 4-Gln-|-His-5, 10-His-|-Leu-11, 14-Ala-|-Leu-15, and 16-Tyr-|-Leu-17 in insulin B chain
Cofactor(s)
Zn(2+).
Comment(s)
  • Endopeptidase from the venom of the king cobra (Ophiophagus hannah).
  • Belongs to peptidase family M12B.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.51
EC2PDB3.4.24.51
ExplorEnz3.4.24.51
PRIAM enzyme-specific profiles3.4.24.51
KEGG Ligand Database for Enzyme Nomenclature3.4.24.51
IUBMB Enzyme Nomenclature3.4.24.51
IntEnz3.4.24.51
MEDLINEFind literature relating to 3.4.24.51
MetaCyc3.4.24.51

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-