ID   3.4.24.56
DE   Insulysin.
AN   Insulin protease.
AN   Insulin-degrading enzyme.
AN   Insulinase.
CA   Degradation of insulin, glucagon and other polypeptides. No action on
CA   proteins.
CF   Zn(2+).
CC   -!- Cytosolic enzyme, known from mammals and Drosophila melanogaster.
CC   -!- Inhibited by bacitracin, chelating agents EDTA and 1,10-
CC       phenanthroline, and by thiol-blocking reagents such as
CC       N-ethylmaleimide, but not by phosphoramidon.
CC   -!- Belongs to peptidase family M16.
CC   -!- Formerly EC 3.4.22.11, EC 3.4.99.10 and EC 3.4.99.45.
PR   PROSITE; PDOC00130;
DR   Q24K02, IDE_BOVIN  ;  P22817, IDE_DROME  ;  P14735, IDE_HUMAN  ;
DR   Q9JHR7, IDE_MOUSE  ;  P35559, IDE_RAT    ;
//