Home  |  Contact
Due to work on this service, it may not be fully operational on Wednesday March 20 between 1.30 pm and 2.30 pm CEST. Apologies for the inconvenience.

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.24.61

Accepted Name
Nardilysin.
Alternative Name(s)
N-arginine dibasic convertase.
NRD convertase.
Reaction catalysed
Hydrolysis of polypeptides, preferably at -Xaa-|-Arg-Lys-, and less commonly at -Arg-|-Arg-Xaa-, in which Xaa is not Arg or Lys
Cofactor(s)
Zn(2+).
Comment(s)
  • Unusually for a metallopeptidase, inhibited by bestatin, amastin and ethylmaleimide.
  • Belongs to peptidase family M16.
Cross-references
PROSITEPDOC00130
BRENDA3.4.24.61
EC2PDB3.4.24.61
ExplorEnz3.4.24.61
PRIAM enzyme-specific profiles3.4.24.61
KEGG Ligand Database for Enzyme Nomenclature3.4.24.61
IUBMB Enzyme Nomenclature3.4.24.61
IntEnz3.4.24.61
MEDLINEFind literature relating to 3.4.24.61
MetaCyc3.4.24.61
UniProtKB/Swiss-Prot
F4HNU6, NRDC_ARATH;  O43847, NRDC_HUMAN;  Q8BHG1, NRDC_MOUSE;  
Q5R4H6, NRDC_PONAB;  P47245, NRDC_RAT;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-