ENZYME entry: EC 3.4.24.61
Accepted Name |
Nardilysin.
|
Alternative Name(s) |
N-arginine dibasic convertase. |
NRD convertase. |
Reaction catalysed |
Hydrolysis of polypeptides, preferably at -Xaa-|-Arg-Lys-, and less commonly at -Arg-|-Arg-Xaa-, in which Xaa is not Arg or Lys |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- Unusually for a metallopeptidase, inhibited by bestatin, amastin and
ethylmaleimide.
- Belongs to peptidase family M16.
|
Cross-references |
PROSITE | PDOC00130 |
BRENDA | 3.4.24.61 |
EC2PDB | 3.4.24.61 |
ExplorEnz | 3.4.24.61 |
PRIAM enzyme-specific profiles | 3.4.24.61 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.61 |
IUBMB Enzyme Nomenclature | 3.4.24.61 |
IntEnz | 3.4.24.61 |
MEDLINE | Find literature relating to 3.4.24.61 |
MetaCyc | 3.4.24.61 |
Rhea expert-curated reactions | 3.4.24.61 |
UniProtKB/Swiss-Prot |
|
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