ENZYME entry: EC 3.4.24.63
Accepted Name |
Meprin B.
|
Reaction catalysed |
Hydrolysis of proteins, including azocasein, and peptides. Hydrolysis of 5-His-|-Leu-6, 6-Leu-|-Cys-7, 14-Ala-|-Leu-15 and 19-Cys-|-Gly-20 bonds in insulin B chain |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- Inhibited by EDTA and 1,10-phenanthroline, but not by phosphoramidon,
captopril or thiorphan.
- Belongs to peptidase family M12A.
|
Cross-references |
PROSITE | PDOC00129 |
BRENDA | 3.4.24.63 |
EC2PDB | 3.4.24.63 |
ExplorEnz | 3.4.24.63 |
PRIAM enzyme-specific profiles | 3.4.24.63 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.63 |
IUBMB Enzyme Nomenclature | 3.4.24.63 |
IntEnz | 3.4.24.63 |
MEDLINE | Find literature relating to 3.4.24.63 |
MetaCyc | 3.4.24.63 |
Rhea expert-curated reactions | 3.4.24.63 |
UniProtKB/Swiss-Prot |
|
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