A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.4.24.69
| Accepted Name |
|---|
| Bontoxilysin.
|
| Alternative Name(s) |
|---|
| Botulinum neurotoxin. |
| Reaction catalysed |
|---|
| Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates |
| Cofactor(s) |
|---|
| Zn(2+).
|
| Comment(s) |
|---|
| Belongs to peptidase family M27.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.69 |
| EC2PDB | 3.4.24.69 |
| ExplorEnz | 3.4.24.69 |
| PRIAM enzyme-specific profiles | 3.4.24.69 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.69 |
| IUBMB Enzyme Nomenclature | 3.4.24.69 |
| IntEnz | 3.4.24.69 |
| MEDLINE | Find literature relating to 3.4.24.69 |
| MetaCyc | 3.4.24.69 |
| UniProtKB/Swiss-Prot |
| P0DPI1, BXA1_CLOBH; | P0DPI0, BXA1_CLOBO; | Q45894, BXA2_CLOBJ; |
| B1INP5, BXB_CLOBK; | P10844, BXB_CLOBO; | P18640, BXC_CBCP; |
| P19321, BXD_CBDP; | Q00496, BXE_CLOBO; | P30995, BXE_CLOBU; |
| A7GBG3, BXF_CLOBL; | P30996, BXF_CLOBO; | Q60393, BXG_CLOBO; |
| A0A242DI27, BXJ_ENTS3; | A0A069CUU9, BXWO_WEIOS; | P0DPK1, BXX_CLOBO; |
|
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UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-