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ENZYME entry: EC 3.4.24.69

Accepted Name
Bontoxilysin.
Alternative Name(s)
Botulinum neurotoxin.
Reaction catalysed
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates
Cofactor(s)
Zn(2+).
Comment(s)
Belongs to peptidase family M27.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.69
EC2PDB3.4.24.69
ExplorEnz3.4.24.69
PRIAM enzyme-specific profiles3.4.24.69
KEGG Ligand Database for Enzyme Nomenclature3.4.24.69
IUBMB Enzyme Nomenclature3.4.24.69
IntEnz3.4.24.69
MEDLINEFind literature relating to 3.4.24.69
MetaCyc3.4.24.69
Rhea expert-curated reactions3.4.24.69
UniProtKB/Swiss-Prot
P0DPI1, BXA1_CLOBH;  P0DPI0, BXA1_CLOBO;  Q45894, BXA2_CLOBJ;  
B1INP5, BXB_CLOBK;  P10844, BXB_CLOBO;  P18640, BXC_CBCP;  
P19321, BXD_CBDP;  Q00496, BXE_CLOBO;  P30995, BXE_CLOBU;  
A7GBG3, BXF_CLOBL;  P30996, BXF_CLOBO;  Q60393, BXG_CLOBO;  
A0A242DI27, BXJ_ENTS3;  A0A069CUU9, BXWO_WEIOS;  P0DPK1, BXX_CLOBO;  

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