A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.24.69

Accepted Name
Bontoxilysin.
Alternative Name(s)
Botulinum neurotoxin.
Reaction catalysed
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates
Cofactor(s)
Zn(2+).
Comment(s)
Belongs to peptidase family M27.
Cross-references
PROSITE	PDOC00129
BRENDA	3.4.24.69
EC2PDB	3.4.24.69
ExplorEnz	3.4.24.69
PRIAM enzyme-specific profiles	3.4.24.69
KEGG Ligand Database for Enzyme Nomenclature	3.4.24.69
IUBMB Enzyme Nomenclature	3.4.24.69
IntEnz	3.4.24.69
MEDLINE	Find literature relating to 3.4.24.69
MetaCyc	3.4.24.69
UniProtKB/Swiss-Prot	P0DPI1, BXA1_CLOBH;   P0DPI0, BXA1_CLOBO;   Q45894, BXA2_CLOBJ;   B1INP5, BXB_CLOBK;   P10844, BXB_CLOBO;   P18640, BXC_CBCP;   P19321, BXD_CBDP;   Q00496, BXE_CLOBO;   P30995, BXE_CLOBU;   A7GBG3, BXF_CLOBL;   P30996, BXF_CLOBO;   Q60393, BXG_CLOBO;   A0A242DI27, BXJ_ENTS3;   A0A069CUU9, BXWO_WEIOS;   P0DPK1, BXX_CLOBO;

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
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